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Pixatimod
Pixatimod is an oligosaccharide pharmaceutical. It is currently being investigated in clinical studies. It is known to target heparanase.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179—1———1
Non-small-cell lung carcinomaD002289—1———1
MelanomaD008545—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePIXATIMOD
INNpixatimod
Description
Pixatimod is an oligosaccharide pharmaceutical. It is currently being investigated in clinical studies. It is known to target heparanase.
Classification
Oligosaccharide
Drug classimmunomodulators
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O[C@@H]5O[C@H](COS(=O)(=O)O)[C@@H](O[C@H]6O[C@H](COS(=O)(=O)O)[C@@H](O[C@H]7O[C@H](COS(=O)(=O)O)[C@@H](O[C@H]8O[C@H](COS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]8OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]7OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]6OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]5OS(=O)(=O)O)CC[C@]4(C)[C@H]3CC[C@@]21C
Identifiers
PDB—
CAS-ID1144492-69-2
RxCUI—
ChEMBL IDCHEMBL2078841
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID66QR34C83N (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HPSE
HPSE
Organism
Homo sapiens
Gene name
HPSE
Gene synonyms
HEP, HPA, HPA1, HPR1, HPSE1, HSE1
NCBI Gene ID
10855
Protein name
heparanase
Protein synonyms
Endo-glucoronidase, Heparanase-1, Hpa1
Uniprot ID
Q9Y251
Mouse ortholog
Hpse (15442)
heparanase (Q8K3K3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 101 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6 adverse events reported
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