Plozalizumab
Plozalizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-C chemokine receptor type 2.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetic nephropathies | D003928 | EFO_0000401 | — | 1 | — | — | — | 1 | |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 1 | — | — | — | 1 |
| Neoplasms | D009369 | C80 | — | 1 | — | — | — | 1 | |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PLOZALIZUMAB |
| INN | plozalizumab |
| Description | Plozalizumab (INN; hu1D9) is a humanized monoclonal antibody designed for the treatment of diabetic nephropathy and arteriovenous graft patency.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1610761-46-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3707228 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12520 |
| UNII ID | 4XG66BMN0D (ChemIDplus, GSRS) |
Target
Agency Approved
CCR2
CCR2
Organism
Homo sapiens
Gene name
CCR2
Gene synonyms
CMKBR2
NCBI Gene ID
Protein name
C-C chemokine receptor type 2
Protein synonyms
CD192, chemokine (C-C motif) receptor 2, MCP-1 receptor, MCP-1-R, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor
Uniprot ID
Mouse ortholog
Ccr2 (12772)
C-C chemokine receptor type 2 (Q61172)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 29 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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