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Polythiazide
Minizide, Renese, Renese-r (polythiazide) is a small molecule pharmaceutical. Polythiazide was first approved as Renese on 1982-01-01. It is used to treat edema, glomerulonephritis, heart failure, hypertension, and liver cirrhosis amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
urogenital diseasesD000091642
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Polythiazide
Tradename
Company
Number
Date
Products
RENESEMylanN-012845 DISCN1982-01-01
3 products
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Polythiazide
+
Prazosin hydrochloride
Tradename
Company
Number
Date
Products
MINIZIDEMylanN-017986 DISCN1982-01-01
3 products
Hide discontinued
Polythiazide
+
Reserpine
Tradename
Company
Number
Date
Products
RENESE-RMylanN-013636 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
edema—D004487R60.9
glomerulonephritis—D005921N05
heart failureEFO_0003144D006333I50
hypertensionEFO_0000537D006973I10
liver cirrhosisEFO_0001422D008103K74.0
nephrotic syndromeEFO_0004255D009404N04
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C03: Diuretics
— C03A: Low-ceiling diuretics, thiazides
— C03AA: Thiazides, plain
— C03AA05: Polythiazide
— C03AB: Thiazides and potassium in combination
— C03AB05: Polythiazide and potassium
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
IschemiaD007511EFO_0000556———112
Intermittent claudicationD007383EFO_0003876I73.9———1—1
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 1 diabetes mellitusD003922EFO_0001359E10—1———1
Tissue adhesionsD000267—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic kidney failureD007676EFO_0003884N18.6————22
Pelvic organ prolapseD056887EFO_0004710————22
Heart failureD006333EFO_0003144I50————11
Drug-related side effects and adverse reactionsD064420T88.7————11
InflammationD007249————11
HemolysisD006461————11
Uterine prolapseD014596EFO_1001864N81.4————11
CystoceleD052858N81.1————11
Peri-implantitisD057873EFO_1001390————11
Diabetes mellitusD003920EFO_0000400E08-E13————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePOLYTHIAZIDE
INNpolythiazide
Description
Polythiazide is a benzothiadiazine.
Classification
Small molecule
Drug classdiuretics (thiazide derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN1C(CSCC(F)(F)F)Nc2cc(Cl)c(S(N)(=O)=O)cc2S1(=O)=O
Identifiers
PDB—
CAS-ID346-18-9
RxCUI8565
ChEMBL IDCHEMBL1587
ChEBI ID8327
PubChem CID4870
DrugBankDB01324
UNII ID36780APV5N (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 147 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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