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Proflavine
Proflavine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
kerr 100 triple dye dispos-aOTC monograph not final2022-11-30
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
18 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C8012——14
Squamous cell neoplasmsD01830712——14
Barrett esophagusD001471EFO_0000280K22.731———4
Uterine neoplasmsD014594EFO_0003859C55—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Uterine cervical neoplasmsD0025831———23
Dentin dysplasiaD003805K00.51————1
Stomach neoplasmsD013274EFO_0003897C161————1
Carcinoma in situD002278D09.91————1
Gastroesophageal refluxD005764EFO_0003948K211————1
Colonic polypsD003111K63.51————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Head and neck neoplasmsD006258————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePROFLAVINE
INNproflavine
Description
3,6-diaminoacridine is an aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds. It has a role as an antiseptic drug, a carcinogenic agent, an antibacterial agent, a chromophore and an intercalator. It is a conjugate base of a 3,6-diaminoacridine(1+).
Classification
Small molecule
Drug classvinca alkaloids
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Nc1ccc2cc3ccc(N)cc3nc2c1
Identifiers
PDB—
CAS-ID92-62-6
RxCUI8723
ChEMBL IDCHEMBL55400
ChEBI ID8452
PubChem CID7099
DrugBankDB01123
UNII IDCY3RNB3K4T (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,465 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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