Propiolactone
Betaprone (propiolactone) is a small molecule pharmaceutical. Propiolactone was first approved as Betaprone on 1982-01-01.
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Abbreviated New Drug Application (ANDA)
Propiolactone
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| BETAPRONE | Forest Laboratories | N-011657 DISCN | 1982-01-01 | 1 products |
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Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | — | 2 | 3 |
| Local anesthesia | D000772 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Corneal injuries | D065306 | HP_0000559 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | — | — | — | 3 | 3 |
| Cataract | D002386 | EFO_0001059 | H26.9 | — | — | — | — | 3 | 3 |
| Macular edema | D008269 | — | — | — | — | 2 | 2 | ||
| Postoperative pain | D010149 | G89.18 | — | — | — | — | 2 | 2 | |
| Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | — | — | — | — | 1 | 1 |
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 1 | 1 | |
| Vitreoretinal surgery | D057586 | — | — | — | — | 1 | 1 | ||
| Anesthesia | D000758 | — | — | — | — | 1 | 1 | ||
| Injection site reaction | D000075662 | — | — | — | — | 1 | 1 | ||
| Angle-closure glaucoma | D015812 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PROPIOLACTONE |
| INN | propiolactone |
| Description | Beta-propiolactone is a propan-3-olide. It is functionally related to a 3-hydroxypropionic acid. It derives from a hydride of an oxetane. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C1CCO1 |
Identifiers
| PDB | — |
| CAS-ID | 57-57-8 |
| RxCUI | 1311565 |
| ChEMBL ID | CHEMBL1200627 |
| ChEBI ID | 49073 |
| PubChem CID | 2365 |
| DrugBank | DB09348 |
| UNII ID | 6RC3ZT4HB0 (ChemIDplus, GSRS) |
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Safety
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382 adverse events reported
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