Skip to content
Propoxyphene
Darvocet, Darvon, Dolene, Kesso-gesic, Prophene, Wygesic (propoxyphene) is a small molecule pharmaceutical. Propoxyphene was first approved as Darvocet on 1982-01-01. It is used to treat pain in the USA.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetaminophen
+
Propoxyphene hydrochloride
Tradename
Company
Number
Date
Products
DARVOCETAAIPharmaN-016844 DISCN1982-01-01
1 products
Hide discontinued
Aspirin
+
Caffeine
+
Propoxyphene hydrochloride
Tradename
Company
Number
Date
Products
DARVON COMPOUNDXanodyne PharmaceuticalsN-010996 DISCN1983-03-08
1 products
DARVON COMPOUND-65Xanodyne PharmaceuticalsN-010996 DISCN1983-03-08
1 products
Hide discontinued
Aspirin
+
Propoxyphene hydrochloride
Tradename
Company
Number
Date
Products
DARVON W/ ASAXanodyne PharmaceuticalsN-010996 DISCN1982-01-01
1 products
Hide discontinued
Propoxyphene hydrochloride
Tradename
Company
Number
Date
Products
DARVONXanodyne PharmaceuticalsN-010997 DISCN1982-01-01
2 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
darvon-nNew Drug Application2009-10-27
propoxyphene napsylate and acetaminophenANDA2011-06-20
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
painEFO_0003843D010146R52
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N02: Analgesics
— N02A: Opioid analgesics
— N02AC: Diphenylpropylamine derivative analgesics
— N02AC04: Dextropropoxyphene
— N02AC54: Dextropropoxyphene, combinations excl. psycholeptics
— N02AC74: Dextropropoxyphene, combinations with psycholeptics
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common namePROPOXYPHENE
INNdextropropoxyphene
Description
Levopropoxyphene is a 1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate. It has a role as an antitussive. It is an enantiomer of a dextropropoxyphene.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCC(=O)O[C@](Cc1ccccc1)(c1ccccc1)[C@H](C)CN(C)C
Identifiers
PDB—
CAS-ID469-62-5
RxCUI6377
ChEMBL IDCHEMBL1213351
ChEBI ID51173
PubChem CID200742
DrugBankDB00647
UNII IDS2F83W92TK (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 2,992 documents
View more details
Safety
Black-box Warning
Black-box warning for: Darvon-n
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
2 adverse events reported
View more details