Razuprotafib
Razuprotafib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target receptor-type tyrosine-protein phosphatase beta.
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COVID-19
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Ocular hypertension | D009798 | EFO_1001069 | H40.0 | 1 | 1 | — | — | — | 2 |
Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | 1 | 1 | — | — | — | 2 |
Covid-19 | D000086382 | U07.1 | — | 1 | — | — | — | 1 | |
Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | — | 1 | — | — | — | 1 |
Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | RAZUPROTAFIB |
INN | razuprotafib |
Description | Razuprotafib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target receptor-type tyrosine-protein phosphatase beta. |
Classification | Small molecule |
Drug class | protein tyrosine phosphatase 1B inhibitors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(=O)(=O)O)cc1)c1csc(-c2cccs2)n1 |
Identifiers
PDB | — |
CAS-ID | 1008510-37-9 |
RxCUI | — |
ChEMBL ID | CHEMBL3931971 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 0WAX4UT396 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
PTPRB
PTPRB
Organism
Homo sapiens
Gene name
PTPRB
Gene synonyms
PTPB
NCBI Gene ID
Protein name
receptor-type tyrosine-protein phosphatase beta
Protein synonyms
protein tyrosine phosphatase, receptor type, beta polypeptide, Vascular endothelial protein tyrosine phosphatase, VE-PTP
Uniprot ID
Mouse ortholog
Ptprb (19263)
receptor-type tyrosine-protein phosphatase beta (Q8CIW2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 36 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,324 adverse events reported
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