Relacorilant
Relacorilant is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Indications
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Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pituitary acth hypersecretion | D047748 | EFO_1001110 | E24.0 | 1 | 2 | 1 | — | — | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | 1 | — | — | 2 |
| Fallopian tube neoplasms | D005185 | — | 1 | 1 | — | — | 2 | ||
| Pancreatic ductal carcinoma | D021441 | — | — | 1 | — | — | 1 | ||
| Cushing syndrome | D003480 | EFO_0003099 | E24 | — | — | 1 | — | — | 1 |
| Peritoneal neoplasms | D010534 | — | — | 1 | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | RELACORILANT |
| INN | relacorilant |
| Description | Relacorilant (developmental code name CORT-125134) is an antiglucocorticoid which is under development by Corcept Therapeutics for the treatment of Cushing's syndrome. It is also under development for the treatment of solid tumors and alcoholism. The drug is a nonsteroidal compound and acts as an antagonist of the glucocorticoid receptor. As of December 2017, it is in phase II clinical trials for Cushing's syndrome and phase I/II clinical studies for solid tumors, while the clinical phase for alcoholism is unknown.
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| Classification | Small molecule |
| Drug class | glucocorticoid receptor antagonists (not glucocorticoids) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cn1cc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C(=O)c3cc(C(F)(F)F)ccn3)C2)cn1 |
Identifiers
| PDB | — |
| CAS-ID | 1496510-51-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4068611 |
| ChEBI ID | — |
| PubChem CID | 73051463 |
| DrugBank | DB14976 |
| UNII ID | 2158753C7E (ChemIDplus, GSRS) |
Target
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