Skip to content
Repotrectinib
Repotrectinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target ALK tyrosine kinase receptor, proto-oncogene tyrosine-protein kinase ROS, NT-3 growth factor receptor, tyrosine-protein kinase JAK2, BDNF/NT-3 growth factors receptor, and high affinity nerve growth factor receptor.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C8044———4
LymphomaD008223C85.911———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD0022891————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameREPOTRECTINIB
INNrepotrectinib
Description
Repotrectinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target ALK tyrosine kinase receptor, proto-oncogene tyrosine-protein kinase ROS, NT-3 growth factor receptor, tyrosine-protein kinase JAK2, BDNF/NT-3 growth factors receptor, and high affinity nerve growth factor receptor.
Classification
Small molecule
Drug classtyrosine kinase inhibitors: tropomyosin receptor kinase (TRK) inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H]1CNC(=O)c2cnn3ccc(nc23)N[C@H](C)c2cc(F)ccc2O1
Identifiers
PDB—
CAS-ID1802220-02-5
RxCUI—
ChEMBL IDCHEMBL4298138
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID08O3FQ4UNP (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ALK
ALK
ROS1
ROS1
NTRK3
NTRK3
JAK2
JAK2
NTRK2
NTRK2
NTRK1
NTRK1
Organism
Homo sapiens
Gene name
ALK
Gene synonyms
NCBI Gene ID
238
Protein name
ALK tyrosine kinase receptor
Protein synonyms
Anaplastic lymphoma kinase, anaplastic lymphoma receptor tyrosine kinase, CD246, CD246 antigen, mutant anaplastic lymphoma kinase
Uniprot ID
Q9Y4K6
Mouse ortholog
Alk (11682)
ALK tyrosine kinase receptor (P97793)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 262 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
View more details