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Revaprazan
Revaprazan is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target potassium-transporting ATPase alpha chain 1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameREVAPRAZAN
INNrevaprazan
Description
Revaprazan is a member of isoquinolines.
Classification
Small molecule
Drug classproton pump inhibitors, not dependent on acid activation
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1nc(Nc2ccc(F)cc2)nc(N2CCc3ccccc3C2C)c1C
Identifiers
PDB—
CAS-ID199463-33-7
RxCUI—
ChEMBL IDCHEMBL1618279
ChEBI ID—
PubChem CID204104
DrugBankDB16308
UNII ID5P184180P5 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ATP4A
ATP4A
Organism
Homo sapiens
Gene name
ATP4A
Gene synonyms
NCBI Gene ID
495
Protein name
potassium-transporting ATPase alpha chain 1
Protein synonyms
ATPase H+/K+ transporting alpha subunit, ATPase, H+/K+ exchanging, alpha polypeptide, ATPase, H+/K+ transporting, alpha polypeptide, epididymis secretory sperm binding protein, Gastric H(+)/K(+) ATPase subunit alpha, gastric H+/K+ ATPase alpha subunit, gastric H,K-ATPase catalytic subunit, gastric hydrogen-potassium ATPase, Proton pump
Uniprot ID
P20648
Mouse ortholog
Atp4a (11944)
potassium-transporting ATPase alpha chain 1 (Q9CV46)
Variants
Clinical Variant
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Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 97 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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