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Rivipansel
Rivipansel is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P-selectin.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sickle cell anemiaD000755EFO_0000697D57122——4
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—4————4
Hepatic insufficiencyD0485501————1
Renal insufficiencyD051437HP_0000083N191————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRIVIPANSEL
INNrivipansel
Description
Rivipansel is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P-selectin.
Classification
Small molecule
Drug classselectin antagonists inhibiting all selectin types
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](NC(=O)c3cc(=O)[nH]c(=O)[nH]3)C[C@@H](C(=O)NCCNC(=O)COCCOCC(=O)Nc3cc(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(S(=O)(=O)O)c34)C[C@H]2O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@H](CC3CCCCC3)C(=O)O)[C@H]2OC(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O
Identifiers
PDB—
CAS-ID1189037-60-2
RxCUI—
ChEMBL IDCHEMBL3707446
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID4B115V09LB (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SELP
SELP
Organism
Homo sapiens
Gene name
SELP
Gene synonyms
GMRP, GRMP
NCBI Gene ID
6403
Protein name
P-selectin
Protein synonyms
CD62 antigen-like family member P, CD62P, GMP-140, Granule membrane protein 140, granule membrane protein 140kDa, granulocyte membrane protein, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, Platelet activation dependent granule-external membrane protein, platelet alpha-granule membrane protein, selectin P (granule membrane protein 140kDa, antigen CD62)
Uniprot ID
P16109
Mouse ortholog
Selp (20344)
P-selectin (Q32MF1)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 114 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6 adverse events reported
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