Rosiptor
Rosiptor is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
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ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | — | 1 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | — | — | — | 1 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | — | — | — | — | 2 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ROSIPTOR |
| INN | rosiptor |
| Description | Rosiptor is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. |
| Classification | Small molecule |
| Drug class | Src homology 2-containing inositol-5' phosphatase 1 (SHIP1) activators |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | C=C1CC[C@H]2[C@H](CN)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CO)CC[C@]12C |
Identifiers
| PDB | — |
| CAS-ID | 782487-28-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3989954 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 6R5034F862 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
INPP5D
INPP5D
Organism
Homo sapiens
Gene name
INPP5D
Gene synonyms
SHIP, SHIP1
NCBI Gene ID
Protein name
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Protein synonyms
hp51CN, Inositol polyphosphate-5-phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa, inositol polyphosphate-5-phosphatase, 145kD, inositol polyphosphate-5-phosphatase, 145kDa, p150Ship, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, SH2 domain-containing inositol 5'-phosphatase 1, SH2 domain-containing inositol phosphatase 1, SHIP-1, signaling inositol polyphosphate 5 phosphatase SIP-145, signaling inositol polyphosphate phosphatase SHIP II, SIP-145
Uniprot ID
Mouse ortholog
Inpp5d (16331)
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (Q9ES52)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 4 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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