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Saralasin
Sarenin (saralasin) is a protein pharmaceutical. Saralasin was first approved as Sarenin on 1982-01-01. It is known to target type-2 angiotensin II receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Saralasin acetate
Tradename
Company
Number
Date
Products
SARENINProcter And GambleN-018009 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471C61231——5
Breast neoplasmsD001943EFO_0003869C50121——3
PainD010146EFO_0003843R52221——3
NeoplasmsD009369C80111——2
Lung neoplasmsD008175C34.90——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Plasma cell neoplasmsD05421943———4
OsteosarcomaD01251611———2
SarcomaD012509—1———1
Neoplasm metastasisD009362EFO_000970811———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSARALASIN
INNsaralasin
Description
Saralasin is an oligopeptide.
Classification
Protein
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C
Identifiers
PDB—
CAS-ID34273-10-4
RxCUI9556
ChEMBL IDCHEMBL938
ChEBI ID—
PubChem CID6324663
DrugBankDB06763
UNII IDH2AFV2HE66 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
AGTR2
AGTR2
Organism
Homo sapiens
Gene name
AGTR2
Gene synonyms
NCBI Gene ID
186
Protein name
type-2 angiotensin II receptor
Protein synonyms
Angiotensin II type-2 receptor, AT2 receptor
Uniprot ID
Q6FGY7
Mouse ortholog
Agtr2 (11609)
type-2 angiotensin II receptor (P35374)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 619 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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143 adverse events reported
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