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Simurosertib
Simurosertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cell division cycle 7-related protein kinase.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179—1———1
Pancreatic neoplasmsD010190EFO_0003860C25—1———1
Non-small-cell lung carcinomaD002289—1———1
Esophageal neoplasmsD004938C15—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C801————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSIMUROSERTIB
INNsimurosertib
Description
Simurosertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cell division cycle 7-related protein kinase.
Classification
Small molecule
Drug classserine/threonine kinase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1n[nH]cc1-c1cc2nc([C@@H]3CC4CCN3CC4)[nH]c(=O)c2s1
Identifiers
PDB—
CAS-ID1330782-76-7
RxCUI—
ChEMBL IDCHEMBL4297644
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDLST350G3XU (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CDC7
CDC7
Organism
Homo sapiens
Gene name
CDC7
Gene synonyms
CDC7L1
NCBI Gene ID
8317
Protein name
cell division cycle 7-related protein kinase
Protein synonyms
CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1, CDC7-related kinase, cell division cycle 7 homolog, cell division cycle 7-like protein 1, epididymis secretory sperm binding protein
Uniprot ID
Q5T5U5
Mouse ortholog
Cdc7 (12545)
cell division cycle 7-related protein kinase (Q9Z2Y7)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 9 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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