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Sodium tetradecyl sulfate
Sotradecol (sodium tetradecyl sulfate) is a small molecule pharmaceutical. Sodium tetradecyl sulfate was first approved as Sotradecol on 1982-01-01. It is used to treat esophageal and gastric varices and varicose veins in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
cardiovascular diseasesD002318
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sodium tetradecyl sulfate
Tradename
Company
Number
Date
Products
SOTRADECOLA.H. Robins CompanyN-005970 DISCN1982-01-01
2 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
sodium tetradecyl sulfateANDA2023-01-10
sotradecolANDA2021-08-17
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
esophageal and gastric varicesEFO_0009545D004932I85
varicose veinsHP_0002619D014648I83.90
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C05: Vasoprotectives
— C05B: Antivaricose therapy drugs
— C05BB: Sclerosing agents for local injection
— C05BB04: Sodium tetradecyl sulfate
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Varicose veinsD014648HP_0002619I83.90———112
Venous insufficiencyD014689—1—1—2
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Epidermal cystD004814K09.8—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PainD010146EFO_0003843R521————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSODIUM TETRADECYL SULFATE
INNsodium tetradecyl sulfate
Description
Sodium tetradecyl sulfate is an organic sodium salt having tetradecyl sulfate as the counterion. Used in the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. It has a role as a detergent and a sclerotherapy agent. It contains a tetradecyl sulfate.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)[O-].[Na+]
Identifiers
PDB—
CAS-ID139-88-8
RxCUI—
ChEMBL IDCHEMBL1200354
ChEBI ID75273
PubChem CID23665772
DrugBankDB00464
UNII IDQ1SUG5KBD6 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,464 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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112 adverse events reported
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