Somatostatin
Somatostatin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
50 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 1 | 6 | 7 |
Portal hypertension | D006975 | EFO_0000666 | K76.6 | 1 | — | 1 | 1 | 2 | 5 |
Acromegaly | D000172 | — | 1 | — | 1 | 2 | 4 | ||
Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | — | — | 1 | 1 | 2 | 4 |
Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | — | — | — | 1 | 3 | 4 |
Healthy volunteers/patients | — | 1 | — | — | 2 | — | 3 | ||
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | 1 | 2 | 3 |
End stage liver disease | D058625 | EFO_1001311 | K72.1 | — | — | — | 1 | — | 1 |
Acute necrotizing pancreatitis | D019283 | — | — | — | 1 | — | 1 | ||
Fibrosis | D005355 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | 2 | — | — | 2 |
Autosomal dominant polycystic kidney | D016891 | EFO_1001496 | Q61.2 | — | — | 1 | — | — | 1 |
Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | — | — | 1 | — | — | 1 |
Malignant carcinoid syndrome | D008303 | E34.0 | — | — | 1 | — | — | 1 | |
Pancreatic diseases | D010182 | K86.9 | — | 1 | 1 | — | — | 1 | |
Liver failure | D017093 | HP_0001399 | K72.9 | — | — | 1 | — | — | 1 |
Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | 1 | 2 |
Carcinoid tumor | D002276 | D3A.00 | — | 1 | — | — | — | 1 | |
Islet cell carcinoma | D018273 | C25.4 | — | 1 | — | — | — | 1 | |
Peptic ulcer | D010437 | HP_0004398 | K27 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypoglycemia | D007003 | HP_0001943 | E16.2 | 1 | — | — | — | 2 | 3 |
Prostatic neoplasms | D011471 | C61 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Glomerular filtration rate | D005919 | EFO_0005208 | — | — | — | — | 1 | 1 | |
Renal circulation | D012079 | — | — | — | — | 1 | 1 | ||
Renal plasma flow | D017595 | — | — | — | — | 1 | 1 | ||
Insulin resistance | D007333 | EFO_0002614 | — | — | — | — | 1 | 1 | |
Glucose intolerance | D018149 | HP_0000833 | R73.03 | — | — | — | — | 1 | 1 |
Laron syndrome | D046150 | Orphanet_633 | E34.321 | — | — | — | — | 1 | 1 |
Acute kidney injury | D058186 | HP_0001919 | N17 | — | — | — | — | 1 | 1 |
Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | — | — | — | 1 | 1 |
Varicose veins | D014648 | HP_0002619 | I83.90 | — | — | — | — | 1 | 1 |
Neuroendocrine carcinoma | D018278 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | SOMATOSTATIN |
INN | somatostatin |
Description | SOMATOSTATIN |
Classification | Protein |
Drug class | growth hormone derivatives; enzyme inhibitors: antihyperlipidemics (HMG-CoA inhibitors) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O |
Identifiers
PDB | — |
CAS-ID | 38916-34-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1823872 |
ChEBI ID | 64628 |
PubChem CID | — |
DrugBank | — |
UNII ID | 6E20216Q0L (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
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Safety
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Adverse Events
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75 adverse events reported
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