Sotatercept
Sotatercept is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
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Indications
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Agency Specific
FDA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pulmonary arterial hypertension | D000081029 | — | 3 | 4 | — | — | 7 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anemia | D000740 | EFO_0004272 | D64.9 | — | 6 | — | — | — | 6 |
| Multiple myeloma | D009101 | C90.0 | 1 | 2 | — | — | — | 3 | |
| Myelodysplastic syndromes | D009190 | D46 | — | 1 | — | — | 1 | 2 | |
| Neoplasms | D009369 | C80 | — | 1 | — | — | — | 1 | |
| Diamond-blackfan anemia | D029503 | D61.01 | 1 | 1 | — | — | — | 1 | |
| Beta-thalassemia | D017086 | Orphanet_848 | D56.1 | — | 1 | — | — | — | 1 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 1 | — | — | — | 1 |
| Myelomonocytic leukemia chronic | D015477 | C93.1 | — | 1 | — | — | — | 1 | |
| Primary myelofibrosis | D055728 | D47.4 | — | 1 | — | — | — | 1 | |
| Non-small-cell lung carcinoma | D002289 | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SOTATERCEPT |
| INN | sotatercept |
| Description | Sotatercept (immunoadhesin) |
| Classification | Protein |
| Drug class | receptor molecules or membrane ligands, natural, modified or modified: transforming growth factor receptors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1743073 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 0QI90BTJ37 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
PubMed Central
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Additional graphs summarizing 387 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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8 adverse events reported
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