Talampanel
Talampanel is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glutamate receptor 2.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | 1 | — | — | — | 3 | ||
| Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | 3 | — | — | — | 3 |
| Dyskinesias | D020820 | G24 | 1 | 2 | — | — | — | 2 | |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | — | — | — | 2 | |
| Movement disorders | D009069 | EFO_0004280 | G25 | 1 | 1 | — | — | — | 1 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | — | 1 | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | — | 1 | — | — | — | 1 | ||
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | — | — | — | 1 | |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | — | — | — | 1 | |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | TALAMPANEL |
| INN | talampanel |
| Description | Talampanel is a member of benzodioxoles. |
| Classification | Small molecule |
| Drug class | ionotropic non-NMDA (N-methyl D-aspartate) glutamate receptors [AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) and/or KA (kainite antagonist) receptors]: antagonists |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2C[C@H]1C)OCO3 |
Identifiers
| PDB | — |
| CAS-ID | 161832-65-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL61872 |
| ChEBI ID | 34992 |
| PubChem CID | 164509 |
| DrugBank | DB04982 |
| UNII ID | CVS43XG1L5 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
GRIA2
GRIA2
Organism
Homo sapiens
Gene name
GRIA2
Gene synonyms
GLUR2
NCBI Gene ID
Protein name
glutamate receptor 2
Protein synonyms
AMPA receptor subunit GluA2, AMPA-selective glutamate receptor 2, GluA2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2
Uniprot ID
Mouse ortholog
Gria2 (14800)
glutamate receptor 2 (P23819)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 269 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more