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Tanzisertib
Tanzisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 9, mitogen-activated protein kinase 8, and mitogen-activated protein kinase 10.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
FibrosisD005355—1———1
Idiopathic pulmonary fibrosisD054990J84.112—1———1
Pulmonary fibrosisD011658J84.10—1———1
Interstitial lung diseasesD017563EFO_0004244J84.89—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTANZISERTIB
INNtanzisertib
Description
Tanzisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 9, mitogen-activated protein kinase 8, and mitogen-activated protein kinase 10.
Classification
Small molecule
Drug classserine/threonine kinase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O[C@H]1CC[C@H](Nc2ncc3nc(Nc4c(F)cc(F)cc4F)n([C@H]4CCOC4)c3n2)CC1
Identifiers
PDB—
CAS-ID1629774-47-5
RxCUI—
ChEMBL IDCHEMBL1950289
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDM5O06306UO (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
MAPK9
MAPK9
MAPK8
MAPK8
MAPK10
MAPK10
Organism
Homo sapiens
Gene name
MAPK9
Gene synonyms
JNK2, PRKM9, SAPK1A
NCBI Gene ID
5601
Protein name
mitogen-activated protein kinase 9
Protein synonyms
c-Jun kinase 2, c-Jun N-terminal kinase 2, JNK-55, Jun kinase, MAP kinase 9, MAPK 9, SAPK1a, Stress-activated protein kinase 1a, Stress-activated protein kinase JNK2
Uniprot ID
P45984
Mouse ortholog
Mapk9 (26420)
mitogen-activated protein kinase 9 (Q9WTU6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 38 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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