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Tarextumab
Tarextumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target neurogenic locus notch homolog protein 2 and neurogenic locus notch homolog protein 3.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pancreatic neoplasmsD010190EFO_0003860C2511———1
Small cell lung carcinomaD05575211———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C801————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTAREXTUMAB
INNtarextumab
Description
Tarextumab (human mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1359940-55-8
RxCUI—
ChEMBL IDCHEMBL3301588
ChEBI ID—
PubChem CID—
DrugBankDB12104
UNII ID333YMY788E (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
NOTCH2
NOTCH2
NOTCH3
NOTCH3
Organism
Homo sapiens
Gene name
NOTCH2
Gene synonyms
NCBI Gene ID
4853
Protein name
neurogenic locus notch homolog protein 2
Protein synonyms
notch 2, Notch homolog 2
Uniprot ID
Q04721
Mouse ortholog
Notch2 (18129)
neurogenic locus notch homolog protein 2 (Q60941)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 198 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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