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Tariquidar
Tariquidar is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target ATP-dependent translocase ABCB1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——2——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C8021———3
Ovarian neoplasmsD010051EFO_0003893C5611———2
Lung neoplasmsD008175C34.9011———2
NeuralgiaD009437EFO_000943021———2
Kidney neoplasmsD007680EFO_0003865C64—1———1
Uterine cervical neoplasmsD002583—1———1
Adrenal cortex neoplasmsD000306C74.0—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SarcomaD0125091————1
Adrenocortical carcinomaD0182681————1
Wilms tumorD0093961————1
Breast neoplasmsD001943EFO_0003869C501————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTARIQUIDAR
INNtariquidar
Description
Tariquidar is a member of benzamides.
Classification
Small molecule
Drug classmultidrug resistance inhibitors: quinoline derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3cc(OC)c(OC)cc3NC(=O)c3cnc4ccccc4c3)cc1)CC2
Identifiers
PDB—
CAS-ID206873-63-4
RxCUI—
ChEMBL IDCHEMBL348475
ChEBI ID—
PubChem CID148201
DrugBankDB06240
UNII IDJ58862DTVD (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ABCB1
ABCB1
Organism
Homo sapiens
Gene name
ABCB1
Gene synonyms
MDR1, PGY1
NCBI Gene ID
5243
Protein name
ATP-dependent translocase ABCB1
Protein synonyms
ATP-binding cassette sub-family B member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CD243, colchicin sensitivity, doxorubicin resistance, Multidrug resistance protein 1, P-glycoprotein 1, Phospholipid transporter ABCB1
Uniprot ID
Q14812
Mouse ortholog
Abcb1b (18669)
ATP-dependent translocase ABCB1 (P06795)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 1,329 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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