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Tinzaparin sodium
Innohep (tinzaparin sodium) is an oligosaccharide pharmaceutical. Tinzaparin sodium was first approved as Innohep on 2000-07-14. It is used to treat pulmonary embolism, thromboembolism, and venous thrombosis in the USA. The pharmaceutical is active against antithrombin-III.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
cardiovascular diseasesD002318
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Tinzaparin sodium
Tradename
Company
Number
Date
Products
INNOHEPLEO PharmaN-020484 DISCN2000-07-14
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
innohep2008-04-14
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
pulmonary embolismEFO_0003827D011655I26
thromboembolismHP_0001907D013923—
venous thrombosisHP_0004936D020246I82.40
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
Code
Description
J1655
Injection, tinzaparin sodium, 1000 iu
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OtosclerosisD010040EFO_0004213H80——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTINZAPARIN SODIUM
INNtinzaparin sodium
Description
Tinzaparin is an antithrombotic drug in the heparin group. It is a low molecular weight heparin (LMWH) marketed as Innohep worldwide. It has been approved by the U.S. Food and Drug Administration (FDA) for once daily treatment and prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE).
Classification
Peptide
Drug classheparin derivatives and low molecular weight (or depolymerized) heparins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID140-10-3
RxCUI—
ChEMBL IDCHEMBL1201414
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID3S182ET3UA (ChemIDplus, GSRS)
Target
Agency Approved
SERPINC1
SERPINC1
Organism
Homo sapiens
Gene name
SERPINC1
Gene synonyms
AT3
NCBI Gene ID
462
Protein name
antithrombin-III
Protein synonyms
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, Serpin C1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Uniprot ID
Q9UC78
Mouse ortholog
Serpinc1 (11905)
antithrombin-III (P32261)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 334 documents
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Safety
Black-box Warning
Black-box warning for: Innohep
Adverse Events
Top Adverse Reactions
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14 adverse events reported
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