Tiratricol
Tiratricol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target thyroid hormone receptor beta and thyroid hormone receptor alpha.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D11: Other dermatological preparations in atc
— D11A: Other dermatological preparations in atc
— D11AX: Other dermatological preparations in atc
— D11AX08: Tiratricol
H: Systemic hormonal preparations, excl. sex hormones and insulins
— H03: Thyroid therapy drugs
— H03A: Thyroid preparations
— H03AA: Thyroid hormones
— H03AA04: Tiratricol
HCPCS
No data
Clinical
Clinical Trials
39 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cough | D003371 | HP_0012735 | R05 | 1 | — | 2 | — | 1 | 4 |
| Hemophilia b | D002836 | D67 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuralgia | D009437 | EFO_0009430 | — | 1 | — | — | — | 1 | |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | — | 1 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | 1 | — | — | — | 1 |
| Common cold | D003139 | EFO_0007214 | J00 | — | 1 | — | — | — | 1 |
| Communicable diseases | D003141 | — | 1 | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 1 | 1 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | — | — | — | — | 1 | 1 |
| Pulmonary fibrosis | D011658 | J84.10 | — | — | — | — | 1 | 1 | |
| Back pain | D001416 | HP_0003418 | M54 | — | — | — | — | 1 | 1 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | TIRATRICOL |
| INN | tiratricol |
| Description | Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. Triiodothyroacetic acid is also a physiologic thyroid hormone that is present in the normal organism in low concentrations.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1 |
Identifiers
| PDB | 1NQ2 |
| CAS-ID | 51-24-1 |
| RxCUI | 13982 |
| ChEMBL ID | CHEMBL41632 |
| ChEBI ID | — |
| PubChem CID | 5803 |
| DrugBank | DB03604 |
| UNII ID | 29OQ9EU4R1 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
THRB
THRB
THRA
THRA
Organism
Homo sapiens
Gene name
THRB
Gene synonyms
ERBA2, NR1A2, THR1
NCBI Gene ID
Protein name
thyroid hormone receptor beta
Protein synonyms
c-erbA-2, c-erbA-beta, Nuclear receptor subfamily 1 group A member 2, oncogene ERBA2, thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
Uniprot ID
Mouse ortholog
Thrb (21834)
thyroid hormone receptor beta (Q3TY80)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 55 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
10 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more