Transplatin
Transplatin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
2874 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | 86 | 222 | 136 | 9 | 13 | 431 | ||
| Head and neck neoplasms | D006258 | 56 | 132 | 51 | 1 | 6 | 222 | ||
| Squamous cell carcinoma of head and neck | D000077195 | 46 | 87 | 36 | 1 | 8 | 161 | ||
| Uterine cervical neoplasms | D002583 | 35 | 63 | 54 | 1 | 11 | 153 | ||
| Esophageal neoplasms | D004938 | C15 | 20 | 89 | 39 | 2 | 6 | 138 | |
| Small cell lung carcinoma | D055752 | 20 | 32 | 21 | 1 | 1 | 66 | ||
| Squamous cell neoplasms | D018307 | 15 | 37 | 10 | 1 | 3 | 58 | ||
| Melanoma | D008545 | 12 | 12 | 6 | 1 | — | 27 | ||
| Adenocarcinoma of lung | D000077192 | 5 | 10 | 2 | 1 | 2 | 20 | ||
| Germ cell and embryonal neoplasms | D009373 | — | 8 | 7 | 1 | 1 | 17 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | C34.90 | 40 | 109 | 53 | — | 3 | 188 | |
| Neoplasms | D009369 | C80 | 126 | 54 | 13 | — | 5 | 176 | |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 34 | 99 | 42 | — | 5 | 164 |
| Nasopharyngeal neoplasms | D009303 | 8 | 64 | 54 | — | 10 | 125 | ||
| Urinary bladder neoplasms | D001749 | C67 | 21 | 65 | 19 | — | 4 | 98 | |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 32 | 37 | 18 | — | 3 | 83 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 19 | 60 | 9 | — | 5 | 83 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 27 | 47 | 6 | — | 1 | 70 |
| Esophageal squamous cell carcinoma | D000077277 | 1 | 40 | 21 | — | 2 | 61 | ||
| Cholangiocarcinoma | D018281 | C22.1 | 19 | 30 | 11 | — | 4 | 56 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peritoneal neoplasms | D010534 | 9 | 10 | — | — | 1 | 19 | ||
| Gastrointestinal neoplasms | D005770 | C26.9 | 3 | 6 | — | — | — | 8 | |
| Large b-cell lymphoma diffuse | D016403 | C83.3 | 2 | 6 | — | — | — | 7 | |
| Thymus neoplasms | D013953 | C37 | 1 | 4 | — | — | — | 4 | |
| B-cell lymphoma | D016393 | 4 | 1 | — | — | — | 4 | ||
| Penile neoplasms | D010412 | C60 | 1 | 3 | — | — | — | 4 | |
| Chondrosarcoma | D002813 | 3 | 1 | — | — | — | 3 | ||
| Digestive system neoplasms | D004067 | 2 | 2 | — | — | — | 3 | ||
| Adenosquamous carcinoma | D018196 | — | 3 | — | — | — | 3 | ||
| Papillomaviridae | D027383 | — | 3 | — | — | — | 3 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Brenner tumor | D001948 | 3 | — | — | — | 1 | 4 | ||
| Cystadenocarcinoma | D003536 | 2 | — | — | — | 1 | 3 | ||
| Appendiceal neoplasms | D001063 | EFO_0003880 | C18.1 | 2 | — | — | — | — | 2 |
| Rhabdomyosarcoma | D012208 | 2 | — | — | — | — | 2 | ||
| Desmoplastic small round cell tumor | D058405 | 2 | — | — | — | — | 2 | ||
| Klatskin tumor | D018285 | EFO_1001005 | 2 | — | — | — | — | 2 | |
| Ampulla of vater cancer | — | 2 | — | — | — | — | 2 | ||
| Castration-resistant prostatic neoplasms | D064129 | 1 | — | — | — | — | 1 | ||
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Pinealoma | D010871 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Circulating neoplastic cells | D009360 | — | — | — | — | 2 | 2 | ||
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 2 | 2 |
| Cervical intraepithelial neoplasia | D018290 | D06 | — | — | — | — | 2 | 2 | |
| Liver transplantation | D016031 | EFO_0010682 | — | — | — | — | 1 | 1 | |
| Prognosis | D011379 | — | — | — | — | 1 | 1 | ||
| Nutritional support | D018529 | — | — | — | — | 1 | 1 | ||
| Virus diseases | D014777 | B34 | — | — | — | — | 1 | 1 | |
| Tumor virus infections | D014412 | — | — | — | — | 1 | 1 | ||
| Otorhinolaryngologic diseases | D010038 | — | — | — | — | 1 | 1 | ||
| Dna virus infections | D004266 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | TRANSPLATIN |
| INN | — |
| Description | trans-Dichlorodiammineplatinum(II) is the trans isomer of the coordination complex with the formula trans-PtCl2(NH3)2, sometimes called transplatin. It is a yellow solid with low solubility in water but good solubility in DMF. The existence of two isomers of PtCl2(NH3)2 led Alfred Werner to propose square planar molecular geometry. It belongs to the molecular symmetry point group D2h.
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| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 14913-33-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1386 |
| ChEBI ID | 27899 |
| PubChem CID | 5702198 |
| DrugBank | DB00515 |
| UNII ID | — |
Target
Agency Approved
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Alternate
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Variants
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Trends
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Safety
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