Trebananib
Trebananib is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against angiopoietin-2.
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
31 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 1 | 3 | — | — | 6 |
| Fallopian tube neoplasms | D005185 | 2 | 1 | 3 | — | — | 6 | ||
| Peritoneal neoplasms | D010534 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 9 | 1 | — | — | — | 10 | |
| Renal cell carcinoma | D002292 | 1 | 3 | — | — | — | 4 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | — | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | 2 | 1 | — | — | — | 3 | |
| Colorectal neoplasms | D015179 | — | 2 | — | — | — | 2 | ||
| Hemangiosarcoma | D006394 | — | 2 | — | — | — | 2 | ||
| Gastrointestinal neoplasms | D005770 | C26.9 | — | 2 | — | — | — | 2 | |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 1 | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | 1 | |
| Gliosarcoma | D018316 | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | C92.0 | 1 | — | — | — | — | 1 | |
| Megakaryoblastic leukemia acute | D007947 | C94.2 | 1 | — | — | — | — | 1 | |
| Monocytic leukemia acute | D007948 | 1 | — | — | — | — | 1 | ||
| Myelomonocytic leukemia acute | D015479 | C92.5 | 1 | — | — | — | — | 1 | |
| Myeloid leukemia | D007951 | C92 | 1 | — | — | — | — | 1 | |
| Erythroblastic leukemia acute | D004915 | EFO_1001257 | C94.0 | 1 | — | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | TREBANANIB |
| INN | trebananib |
| Description | Trebananib (mab) |
| Classification | Protein |
| Drug class | angiogenesis inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108568 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | X8Y5U6NC7E (ChemIDplus, GSRS) |
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Safety
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Adverse Events
Top Adverse Reactions
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59 adverse events reported
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