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Trevogrumab
Trevogrumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against growth/differentiation factor 8.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Inclusion body myositisD018979EFO_0007323G72.4111
SarcopeniaD055948EFO_1000653M62.8411
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients55
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTREVOGRUMAB
INNtrevogrumab
Description
Trevogrumab (INN; development code REGN1033) is a human monoclonal antibody designed for the treatment of muscle atrophy due to orthopedic disuse and sarcopenia.
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL3545374
ChEBI ID
PubChem CID
DrugBank
UNII ID87T4327873 (ChemIDplus, GSRS)
Target
Agency Approved
MSTN
MSTN
Organism
Homo sapiens
Gene name
MSTN
Gene synonyms
GDF8
NCBI Gene ID
Protein name
growth/differentiation factor 8
Protein synonyms
Myostatin, myostatin-b
Uniprot ID
Mouse ortholog
Mstn (17700)
growth/differentiation factor 8 (O08689)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 21 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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