Triamcinolone hexacetonide
Aristospan (triamcinolone hexacetonide) is a small molecule pharmaceutical. Triamcinolone hexacetonide was first approved as Aristospan on 1982-01-01. It is used to treat adrenal insufficiency, allergic rhinitis perennial, ankylosing spondylitis, atopic dermatitis, and berylliosis amongst others in the USA.
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Therapeutic Areas
Therapeutic Area | MeSH |
---|---|
infections | D007239 |
musculoskeletal diseases | D009140 |
digestive system diseases | D004066 |
respiratory tract diseases | D012140 |
otorhinolaryngologic diseases | D010038 |
nervous system diseases | D009422 |
eye diseases | D005128 |
urogenital diseases | D000091642 |
hemic and lymphatic diseases | D006425 |
hereditary congenital and neonatal diseases and abnormalities | D009358 |
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Triamcinolone hexacetonide
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ARISTOSPAN | Sandoz | N-016466 DISCN | 1982-01-01 | 2 products, RLD |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
---|---|---|
hexatrione | unapproved drug for use in drug shortage | 2021-02-23 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
adrenal insufficiency | — | D000309 | — |
allergic rhinitis perennial | EFO_1001417 | D012221 | J30.89 |
ankylosing spondylitis | EFO_0003898 | D013167 | M45 |
atopic dermatitis | EFO_0000274 | D003876 | L20 |
berylliosis | EFO_0007168 | D001607 | J63.2 |
bronchial spasm | — | D001986 | — |
dermatitis herpetiformis | — | D003874 | L13.0 |
erythema multiforme | — | D004892 | L51 |
facial dermatoses | — | D005148 | — |
foot dermatoses | — | D005533 | — |
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
Code | Description |
---|---|
J3303 | Injection, triamcinolone hexacetonide, per 5 mg |
Clinical
Clinical Trials
575 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular edema | D008269 | 8 | 11 | 20 | 4 | 10 | 50 | ||
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 4 | 2 | 12 | 5 | 24 |
Macular degeneration | D008268 | EFO_0001365 | H35.30 | 3 | 4 | 8 | 1 | 3 | 17 |
Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | 2 | 4 | 5 | 1 | 5 | 16 |
Alopecia areata | D000506 | EFO_0004192 | L63 | 1 | 3 | — | 6 | 4 | 13 |
Keloid | D007627 | EFO_0004212 | L91.0 | 1 | 2 | 1 | 3 | 6 | 12 |
Oral lichen planus | D017676 | 3 | 4 | 1 | 2 | 2 | 12 | ||
Shoulder pain | D020069 | HP_0030834 | M25.51 | — | 3 | — | 3 | 4 | 10 |
Carpal tunnel syndrome | D002349 | EFO_0004143 | G56.0 | — | 1 | 2 | 1 | 7 | 10 |
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 3 | — | 4 | 2 | 9 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Diabetic retinopathy | D003930 | EFO_0003770 | 5 | 5 | 4 | — | — | 11 | |
Bursitis | D002062 | EFO_1000941 | M71.9 | 1 | — | 2 | — | 8 | 11 |
Cataract | D002386 | EFO_0001059 | H26.9 | — | 2 | 3 | — | 4 | 8 |
Gouty arthritis | D015210 | — | 1 | 3 | — | — | 4 | ||
Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | — | — | 1 | — | 2 | 3 |
Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 1 | — | 1 | 3 |
Vitiligo | D014820 | EFO_0004208 | L80 | — | 2 | 1 | — | 1 | 3 |
Ischemic optic neuropathy | D018917 | EFO_1000809 | H47.01 | 1 | 1 | 1 | — | — | 2 |
Chemotherapy-induced febrile neutropenia | D064146 | — | 1 | 1 | — | — | 2 | ||
Liver transplantation | D016031 | EFO_0010682 | — | — | 2 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | 1 | — | — | 12 | 13 |
Cognitive dysfunction | D060825 | G31.84 | 2 | 2 | — | — | 6 | 9 | |
Kidney transplantation | D016030 | 1 | 5 | — | — | — | 5 | ||
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 4 | — | — | — | 4 |
T-cell lymphoma cutaneous | D016410 | C84.A | 1 | 1 | — | — | 1 | 3 | |
Psoriasis | D011565 | EFO_0000676 | L40 | 1 | 2 | — | — | — | 3 |
Transcranial direct current stimulation | D065908 | 1 | 1 | — | — | 2 | 3 | ||
Asthma | D001249 | EFO_0000270 | J45 | — | 1 | — | — | 2 | 3 |
Therapeutics | D013812 | — | 1 | — | — | 1 | 2 | ||
Melanoma | D008545 | — | 1 | — | — | 1 | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | — | — | — | 7 | 8 |
Cicatrix | D002921 | HP_0100699 | L90.5 | 1 | — | — | — | 2 | 3 |
Neuralgia | D009437 | EFO_0009430 | 1 | — | — | — | 1 | 2 | |
Leiomyoma | D007889 | HP_0000131 | D25 | 1 | — | — | — | — | 1 |
Adenomyosis | D062788 | EFO_1001757 | N80.0 | 1 | — | — | — | — | 1 |
Humeral fractures | D006810 | EFO_0003943 | S42.3 | 1 | — | — | — | — | 1 |
Vasoconstriction | D014661 | 1 | — | — | — | — | 1 | ||
Papilledema | D010211 | EFO_1001074 | H35.81 | 1 | — | — | — | — | 1 |
Acoustic neuroma | D009464 | HP_0009588 | 1 | — | — | — | — | 1 | |
Drug interactions | D004347 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | — | — | 7 | 7 | ||
Memory disorders | D008569 | — | — | — | — | 4 | 4 | ||
Dementia | D003704 | F03 | — | — | — | — | 4 | 4 | |
Psychotic disorders | D011618 | F20.81 | — | — | — | — | 3 | 3 | |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | — | — | 3 | 3 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 3 | 3 |
Skin diseases | D012871 | L00-L99 | — | — | — | — | 3 | 3 | |
Hemianopsia | D006423 | H53.46 | — | — | — | — | 2 | 2 | |
Essential tremor | D020329 | EFO_0003108 | G25.0 | — | — | — | — | 2 | 2 |
Frontotemporal dementia | D057180 | G31.0 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | TRIAMCINOLONE HEXACETONIDE |
INN | triamcinolone hexacetonide |
Description | Triamcinolone hexacetonide is a corticosteroid hormone. |
Classification | Small molecule |
Drug class | steroids (not prednisolone derivatives); topical steroids (acetal derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C |
Identifiers
PDB | — |
CAS-ID | 5611-51-8 |
RxCUI | 38546 |
ChEMBL ID | CHEMBL1200878 |
ChEBI ID | 9670 |
PubChem CID | 21826 |
DrugBank | — |
UNII ID | I7GT1U99Y9 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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15,709 adverse events reported
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