Tridihexethyl
Pathilon (tridihexethyl) is a small molecule pharmaceutical. Tridihexethyl was first approved as Pathilon on 1982-01-01.
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New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Indications
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Clinical
Clinical Trials
167 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental plaque | D003773 | — | 1 | 10 | 3 | 1 | 15 | ||
| Acne vulgaris | D000152 | EFO_0003894 | L70 | 1 | 1 | 1 | 7 | 1 | 10 |
| Facial pain | D005157 | R51.9 | 1 | 3 | 1 | 1 | 5 | 9 | |
| Gingivitis | D005891 | K05.10 | — | — | 2 | 6 | 1 | 9 | |
| Surgical wound infection | D013530 | — | — | 2 | 3 | 1 | 6 | ||
| Periodontal diseases | D010510 | K05.6 | — | — | 3 | 1 | 1 | 5 | |
| Melanosis | D008548 | EFO_0003963 | L81.1 | 1 | — | — | 1 | 1 | 3 |
| Seborrheic dermatitis | D012628 | L21 | — | — | — | 1 | 1 | 2 | |
| Aggressive periodontitis | D010520 | EFO_0006342 | K05.2 | — | — | — | 1 | — | 1 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Temporomandibular joint disorders | D013705 | M26.6 | 3 | 3 | 3 | — | 12 | 18 | |
| Gingival diseases | D005882 | K05.1 | — | — | 6 | — | — | 6 | |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 2 | 1 | — | 1 | 4 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | 1 | 1 | 1 | — | — | 2 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | 1 | — | 1 | 2 | |
| Covid-19 | D000086382 | U07.1 | — | 1 | 1 | — | — | 2 | |
| Infertility | D007246 | EFO_0000545 | — | 1 | 1 | — | — | 1 | |
| Electromyography | D004576 | — | 1 | 1 | — | — | 1 | ||
| Cannabis | D002188 | — | 1 | 1 | — | — | 1 | ||
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | 1 | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 4 | 4 |
| Bruxism | D002012 | F45.8 | — | — | — | — | 3 | 3 | |
| Myalgia | D063806 | HP_0003326 | M79.1 | — | — | — | — | 2 | 2 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 2 | 2 |
| Personal satisfaction | D010549 | — | — | — | — | 2 | 2 | ||
| Chronic pain | D059350 | HP_0012532 | — | — | — | — | 2 | 2 | |
| Pulpitis | D011671 | EFO_1001139 | K04.0 | — | — | — | — | 2 | 2 |
| Postoperative pain | D010149 | G89.18 | — | — | — | — | 2 | 2 | |
| Edentulous jaw | D007575 | — | — | — | — | 2 | 2 | ||
| Edentulous mouth | D009066 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | TRIDIHEXETHYL |
| INN | — |
| Description | Tridihexethyl is a tertiary alcohol and a quaternary ammonium ion. It has a role as an anti-ulcer drug, a muscarinic antagonist and an antispasmodic drug. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC[N+](CC)(CC)CCC(O)(c1ccccc1)C1CCCCC1 |
Identifiers
| PDB | — |
| CAS-ID | 60-49-1 |
| RxCUI | 38617 |
| ChEMBL ID | CHEMBL1201354 |
| ChEBI ID | 9701 |
| PubChem CID | 20299 |
| DrugBank | DB00505 |
| UNII ID | — |
Target
Agency Approved
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Variants
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Trends
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Additional graphs summarizing 24 documents
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Safety
Black-box Warning
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Adverse Events
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868 adverse events reported
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