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Trimethadione
Tridione (trimethadione) is a small molecule pharmaceutical. Trimethadione was first approved as Tridione on 1982-01-01. It is used to treat absence epilepsy and epilepsy in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Trimethadione
Tradename
Company
Number
Date
Products
TRIDIONEAbbVieN-005856 DISCN1982-01-01
3 products, RLD
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
absence epilepsyHP_0011147D004832G40.A
epilepsyEFO_0000474D004827G40.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N03: Antiepileptics
— N03A: Antiepileptics
— N03AC: Oxazolidine derivatives, antiepileptics
— N03AC02: Trimethadione
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTRIMETHADIONE
INNtrimethadione
Description
Trimethadione is an oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent. It has a role as a geroprotector and an anticonvulsant.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN1C(=O)OC(C)(C)C1=O
Identifiers
PDB—
CAS-ID127-48-0
RxCUI10827
ChEMBL IDCHEMBL695
ChEBI ID—
PubChem CID5576
DrugBankDB00347
UNII IDR7GV3H6FQ4 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 523 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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724 adverse events reported
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