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Trimethaphan camsylate
Arfonad (trimethaphan camsylate) is a small molecule pharmaceutical. Trimethaphan camsylate was first approved as Arfonad on 1982-01-01. It is used to treat aortic aneurysm, malignant hypertension, and pulmonary edema in the USA.
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Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
cardiovascular diseasesD002318
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Trimethaphan camsylate
Tradename
Company
Number
Date
Products
ARFONADRocheN-008983 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
aortic aneurysmEFO_0001666D001014I71.9
malignant hypertensionEFO_1001031D006974—
pulmonary edemaEFO_1001134D011654J81
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTRIMETHAPHAN CAMSYLATE
INNtrimetaphan camsilate
Description
Trimethaphan camsylate is the (S)-camphorsulfonate salt of trimethaphan. It has a role as an antihypertensive agent. It contains a trimethaphan and a (S)-camphorsulfonate.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC1(C)C2CCC1(CS(=O)(=O)[O-])C(=O)C2.O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1
Identifiers
PDB—
CAS-ID68-91-7
RxCUI—
ChEMBL IDCHEMBL1245
ChEBI ID—
PubChem CID44602409
DrugBankDBSALT001381
UNII ID8W556014K9 (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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27 adverse events reported
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