Skip to content
Tropisetron
Tropisetron is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target glycine receptor subunit alpha-2, 5-hydroxytryptamine receptor 4, glycine receptor subunit beta, and glycine receptor subunit alpha-1.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A04: Antiemetics and antinauseants
— A04A: Antiemetics and antinauseants
— A04AA: Serotonin (5ht3) antagonists
— A04AA03: Tropisetron
HCPCS
No data
Clinical
Clinical Trials
19 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
VomitingD014839HP_0002013R11.11233110
Postoperative nausea and vomitingD020250EFO_0004888———123
NauseaD009325HP_0002018R11.0—1—1—2
PainD010146EFO_0003843R52—1—1—2
DeliriumD003693R41.0———2—2
Postoperative cognitive complicationsD000079690———1—1
Emergence deliriumD000071257———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179——1——1
SchizophreniaD012559EFO_0000692F20——1——1
Smoking cessationD016540EFO_0004319——1——1
Uterine cervical neoplasmsD002583——1——1
Nasopharyngeal neoplasmsD009303——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C80—1———1
Liver neoplasmsD008113EFO_1001513C22.0—1———1
Chronic diseaseD002908—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnalgesiaD000698————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameTROPISETRON
INNtropisetron
Description
Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.
Classification
Small molecule
Drug classserotonin 5-HT3 receptor antagonists; atropine derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)c1c[nH]c3ccccc13)C2
Identifiers
PDB—
CAS-ID89565-68-4
RxCUI27392
ChEMBL IDCHEMBL56564
ChEBI ID32269
PubChem CID72165
DrugBankDB11699
UNII ID6I819NIK1W (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GLRA2
GLRA2
HTR4
HTR4
GLRB
GLRB
GLRA1
GLRA1
Organism
Homo sapiens
Gene name
GLRA2
Gene synonyms
NCBI Gene ID
2742
Protein name
glycine receptor subunit alpha-2
Protein synonyms
glycine receptor alpha 2 subunit, glycine receptor, alpha-2 polypeptide
Uniprot ID
Q99862
Mouse ortholog
Glra2 (237213)
glycine receptor subunit alpha-2 (Q7TNC8)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,864 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
78 adverse events reported
View more details