Skip to content
Tubocurarine
Tubocurarine is a small molecule pharmaceutical. Tubocurarine was first approved as Tubocurarine chloride on 1982-01-01. It is known to target small conductance calcium-activated potassium channel protein 2, zinc-activated ligand-gated ion channel, small conductance calcium-activated potassium channel protein 1, 5-hydroxytryptamine receptor 3A, and small conductance calcium-activated potassium channel protein 3.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Tubocurarine chloride
Tradename
Company
Number
Date
Products
TUBOCURARINE CHLORIDEBristol Myers SquibbN-005657 DISCN1982-01-01
1 products
TUBOCURARINE CHLORIDEHospiraN-006095 DISCN1982-01-01
1 products
TUBOCURARINE CHLORIDEEli LillyN-006325 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M03: Muscle relaxants
— M03A: Muscle relaxants, peripherally acting agents
— M03AA: Curare alkaloid muscle relaxants, peripherally acting
— M03AA02: Tubocurarine
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SepsisD018805A41.9————11
BacteremiaD016470EFO_0003033R78.81————11
EndocarditisD004696EFO_0000465I33————11
Staphylococcus aureusD013211NCBITaxon_1280————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameTUBOCURARINE
INNtubocurarine chloride
Description
Tubocurarine is a benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare. It has a role as a nicotinic antagonist, a muscle relaxant and a drug allergen. It derives from a hydride of a tubocuraran.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1cc2c3cc1Oc1cc(ccc1O)C[C@@H]1c4c(cc(OC)c(O)c4Oc4ccc(cc4)C[C@@H]3N(C)CC2)CC[N+]1(C)C
Identifiers
PDB2XYT
CAS-ID57-95-4
RxCUI10917
ChEMBL IDCHEMBL339427
ChEBI ID9774
PubChem CID6000
DrugBankDB01199
UNII ID7BCM17J5YA (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
KCNN2
KCNN2
ZACN
ZACN
KCNN1
KCNN1
HTR3A
HTR3A
KCNN3
KCNN3
Organism
Homo sapiens
Gene name
KCNN2
Gene synonyms
NCBI Gene ID
3781
Protein name
small conductance calcium-activated potassium channel protein 2
Protein synonyms
apamin-sensitive small-conductance Ca2+-activated potassium channel, KCa2.2, potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, small conductance calcium-activated potassium channel 2
Uniprot ID
Q9H2S1
Mouse ortholog
Kcnn2 (140492)
small conductance calcium-activated potassium channel protein 2 (P58390)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 5,746 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
34 adverse events reported
View more details