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Tyropanoic acid
Bilopaque (tyropanoic acid) is a small molecule pharmaceutical. Tyropanoic acid was first approved as Bilopaque on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Tyropanoate sodium
Tradename
Company
Number
Date
Products
BILOPAQUEGE HealthcareN-013731 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
V: Various drug classes in atc
— V08: Contrast media
— V08A: X-ray contrast media, iodinated
— V08AC: Watersoluble, hepatotropic x-ray contrast media
— V08AC09: Tyropanoic acid
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9———1—1
Chronic bronchitisD029481J42———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bronchopulmonary dysplasiaD001997P27.8—11——1
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTYROPANOIC ACID
INNsodium tyropanoate
Description
Tyropanoic acid and its salt sodium tyropanoate are radiocontrast agents used in cholecystography (X-ray diagnosis of gallstones). Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. This molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the bile.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCC(=O)Nc1c(I)cc(I)c(CC(CC)C(=O)O)c1I
Identifiers
PDB—
CAS-ID27293-82-9
RxCUI10960
ChEMBL IDCHEMBL1201261
ChEBI ID—
PubChem CID5611
DrugBankDB09340
UNII IDXRJ0P5FAYO (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 10 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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