Vantictumab
Vantictumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target frizzled-7, frizzled-8, frizzled-1, frizzled-5, and frizzled-2.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 2 | — | — | — | — | 2 | |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | VANTICTUMAB |
| INN | vantictumab |
| Description | Vantictumab (human mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1345009-45-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2364652 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12956 |
| UNII ID | 88WBI2D80S (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
FZD7
FZD7
FZD8
FZD8
FZD1
FZD1
FZD5
FZD5
FZD2
FZD2
Organism
Homo sapiens
Gene name
FZD7
Gene synonyms
NCBI Gene ID
Protein name
frizzled-7
Protein synonyms
frizzled 7, seven transmembrane spanning receptor, frizzled family receptor 7, frizzled homolog 7, Frizzled, drosophila, homolog of, 7, fz-7, FzE3, hFz7
Uniprot ID
Mouse ortholog
Fzd7 (14369)
frizzled-7 (Q61090)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 267 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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