Verinurad
Verinurad is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target solute carrier family 22 member 12.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
22 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gout | D006073 | EFO_0004274 | M10 | 5 | 3 | — | — | — | 8 |
| Chronic renal insufficiency | D051436 | N18 | 4 | 1 | — | — | — | 5 | |
| Asymptomatic diseases | D058070 | 1 | 2 | — | — | — | 2 | ||
| Hyperuricemia | D033461 | — | 2 | — | — | — | 2 | ||
| Albuminuria | D000419 | EFO_0004285 | R80.9 | — | 1 | — | — | — | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | — | 1 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 4 | — | — | — | — | 4 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | VERINURAD |
| INN | verinurad |
| Description | Verinurad is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target solute carrier family 22 member 12. |
| Classification | Small molecule |
| Drug class | urate transporter inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 1352792-74-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3707347 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 12WJ62D047 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
SLC22A12
SLC22A12
Organism
Homo sapiens
Gene name
SLC22A12
Gene synonyms
OATL4, URAT1
NCBI Gene ID
Protein name
solute carrier family 22 member 12
Protein synonyms
Organic anion transporter 4-like protein, Renal-specific transporter, RST, solute carrier family 22 (organic anion/cation transporter), member 12, solute carrier family 22 (organic anion/urate transporter), member 12, URAT1, Urate anion exchanger 1, urate anion transporter 1, urate transporter 1, Urate:anion antiporter SLC22A12
Uniprot ID
Mouse ortholog
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Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 71 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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