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Vernakalant
Brinavess (vernakalant) is a small molecule pharmaceutical. Vernakalant was first approved as Brinavess on 2010-09-01. It has been approved in Europe to treat atrial fibrillation.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C01: Cardiac therapy drugs
— C01B: Antiarrhythmics, class i and iii
— C01BG: Other antiarrhythmics, class i and iii in atc
— C01BG11: Vernakalant
HCPCS
No data
Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atrial fibrillationD001281EFO_0000275I48.0—285116
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atrial flutterD001282EFO_0003911—13——3
Indications Phases 2
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Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVERNAKALANT
INNvernakalant
Description
Vernakalant is an alcohol and a member of phenols.
Classification
Small molecule
Drug classpotassium channel antagonists: mixed sodium/potassium channel blockers
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)cc1OC
Identifiers
PDB—
CAS-ID794466-70-9
RxCUI—
ChEMBL IDCHEMBL2111112
ChEBI ID—
PubChem CID9930049
DrugBankDB06217
UNII ID9G468C8B13 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 358 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6 adverse events reported
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