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Zanolimumab
Zanolimumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target T-cell surface glycoprotein CD4.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.9—11——1
Sezary syndromeD012751C84.1——1——1
Mycosis fungoidesD009182C84.0——1——1
T-cell lymphomaD016399—11——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
T-cell lymphoma cutaneousD016410C84.A—2———2
MelanomaD008545—1———1
Kidney neoplasmsD007680EFO_0003865C64—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameZANOLIMUMAB
INNzanolimumab
Description
Zanolimumab (human mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID652153-01-0
RxCUI—
ChEMBL IDCHEMBL2108063
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDHG3L8885M0 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CD4
CD4
Organism
Homo sapiens
Gene name
CD4
Gene synonyms
NCBI Gene ID
920
Protein name
T-cell surface glycoprotein CD4
Protein synonyms
CD4, CD4 antigen (p55), CD4 receptor, T-cell surface antigen T4/Leu-3
Uniprot ID
Q9UDE5
Mouse ortholog
Cd4 (12504)
T-cell surface glycoprotein CD4 (P06332)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 97 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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