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Zavegepant
Zavzpret (zavegepant) is a small molecule pharmaceutical. Zavegepant was first approved as Zavzpret on 2023-03-09. It is known to target calcitonin gene-related peptide type 1 receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Zavzpret
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Zavegepant hydrochloride
Tradename
Company
Number
Date
Products
ZAVZPRETMylanN-216386 RX2023-03-09
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
zavzpretNew Drug Application2023-03-09
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration
Code
ZAVEGEPANT HYDROCHLORIDE, ZAVZPRET, PFIZER
2028-03-09NCE
Patent Expiration
Patent
Expires
Flag
FDA Information
Zavegepant Hydrochloride, Zavzpret, Pfizer
84815462031-10-07DS, DPU-3555
72208622024-01-21DS, DP
73148832023-12-05U-3555
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Migraine disordersD008881EFO_0003821G43—23——3
Covid-19D000086382U07.1—11——1
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J451————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameZAVEGEPANT
INNzavegepant
Description
Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. Zavegepant is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer.
Classification
Small molecule
Drug classcalcitonin gene-related peptide receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1cc(C[C@@H](NC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)N2CCN(C3CCN(C)CC3)CC2)cc2cn[nH]c12
Identifiers
PDB—
CAS-ID1337918-83-8
RxCUI—
ChEMBL IDCHEMBL2397415
ChEBI ID—
PubChem CID53472683
DrugBankDB15688
UNII IDODU3ZAZ94J (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CALCRL
CALCRL
Organism
Homo sapiens
Gene name
CALCRL
Gene synonyms
CGRPR
NCBI Gene ID
10203
Protein name
calcitonin gene-related peptide type 1 receptor
Protein synonyms
calcitonin receptor-like, Calcitonin receptor-like receptor, CGRP type 1 receptor
Uniprot ID
Q53TS5
Mouse ortholog
Calcrl (54598)
calcitonin gene-related peptide type 1 receptor (Q9WUP2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 33 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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