Ziltivekimab
Ziltivekimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target IgG receptor FcRn large subunit p51 and interleukin-6.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic renal insufficiency | D051436 | N18 | 2 | 2 | 1 | — | — | 5 | |
| Inflammation | D007249 | — | 2 | 1 | — | — | 3 | ||
| Heart disease risk factors | D000082742 | — | 1 | 1 | — | — | 2 | ||
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anemia | D000740 | EFO_0004272 | D64.9 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ZILTIVEKIMAB |
| INN | ziltivekimab |
| Description | Ziltivekimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target IgG receptor FcRn large subunit p51 and interleukin-6. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297732 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | AN3Y2B4SX4 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
FCGRT
FCGRT
IL6
IL6
Organism
Homo sapiens
Gene name
FCGRT
Gene synonyms
FCRN
NCBI Gene ID
Protein name
IgG receptor FcRn large subunit p51
Protein synonyms
Fc fragment of IgG receptor and transporter, Fc fragment of IgG, receptor, transporter, alpha, FcRn alpha chain, heavy chain of the major histocompatibility complex class I-like Fc receptor, IgG Fc fragment receptor transporter alpha chain, immunoglobulin receptor, intestinal, heavy chain, major histocompatibility complex class I-like Fc receptor, Neonatal Fc receptor, neonatal Fc-receptor for Ig, transmembrane alpha chain of the neonatal receptor
Uniprot ID
Mouse ortholog
Fcgrt (14132)
IgG receptor FcRn large subunit p51 (Q9R2A5)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 121 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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