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Zimlovisertib
Zimlovisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-1 receptor-associated kinase 4.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Mock data
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.9—2———2
Covid-19D000086382U07.1—1———1
Hidradenitis suppurativaD017497L73.2—1———1
PneumoniaD011014EFO_0003106J18—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—7————7
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameZIMLOVISERTIB
INNzimlovisertib
Description
Zimlovisertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-1 receptor-associated kinase 4.
Classification
Small molecule
Drug classserine/threonine kinase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC[C@H]1[C@@H](COc2nccc3cc(C(N)=O)c(OC)cc23)NC(=O)[C@H]1F
Identifiers
PDB—
CAS-ID1817626-54-2
RxCUI—
ChEMBL IDCHEMBL4081711
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDS3F315JJXI (ChemIDplus, GSRS)
Target
Agency Approved
IRAK4
IRAK4
Organism
Homo sapiens
Gene name
IRAK4
Gene synonyms
NCBI Gene ID
51135
Protein name
interleukin-1 receptor-associated kinase 4
Protein synonyms
Renal carcinoma antigen NY-REN-64
Uniprot ID
Q9Y589
Mouse ortholog
Irak4 (266632)
interleukin-1 receptor-associated kinase 4 (Q8R4K2)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 8 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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