Skip to content
Ziritaxestat
Ziritaxestat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against ectonucleotide pyrophosphatase/phosphodiesterase family member 2.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Idiopathic pulmonary fibrosisD054990J84.112—12——3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Systemic sclerodermaD012595EFO_0000717M34—2———2
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—4————4
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameZIRITAXESTAT
INNziritaxestat
Description
Ziritaxestat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against ectonucleotide pyrophosphatase/phosphodiesterase family member 2.
Classification
Small molecule
Drug classenzyme inhibitors: autotaxin inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCc1nc2c(C)cc(N3CCN(CC(=O)N4CC(O)C4)CC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)c(C#N)s1
Identifiers
PDB—
CAS-ID1628260-79-6
RxCUI—
ChEMBL IDCHEMBL3828074
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDI02418V13W (ChemIDplus, GSRS)
Target
Agency Approved
ENPP2
ENPP2
Organism
Homo sapiens
Gene name
ENPP2
Gene synonyms
ATX, PDNP2
NCBI Gene ID
5168
Protein name
ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Protein synonyms
Autotaxin, autotaxin-t, E-NPP 2, Extracellular lysophospholipase D, LysoPLD, phosphodiesterase I/nucleotide pyrophosphatase 2, plasma lysophospholipase D
Uniprot ID
Q9UCR4
Mouse ortholog
Enpp2 (18606)
ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Q9R1E6)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 31 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
View more details