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Zucapsaicin
Zucapsaicin is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target transient receptor potential cation channel subfamily V member 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M02: Topical products for joint and muscular pain
— M02A: Topical products for joint and muscular pain
— M02AB: Capsaicin and similar agents
— M02AB02: Zucapsaicin
HCPCS
No data
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cluster headacheD003027HP_0012199G44.00——3——3
Knee osteoarthritisD020370EFO_0004616M17——2——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postherpetic neuralgiaD051474—2———2
Dry eye syndromesD015352H04.12—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—2————2
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameZUCAPSAICIN
INNzucapsaicin
Description
Zucapsaicin is a member of phenols and a member of methoxybenzenes.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1cc(CNC(=O)CCCC/C=C\C(C)C)ccc1O
Identifiers
PDB—
CAS-ID25775-90-0
RxCUI—
ChEMBL IDCHEMBL313971
ChEBI ID—
PubChem CID1548942
DrugBankDB09120
UNII ID15OX67P384 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
TRPV1
TRPV1
Organism
Homo sapiens
Gene name
TRPV1
Gene synonyms
VR1
NCBI Gene ID
7442
Protein name
transient receptor potential cation channel subfamily V member 1
Protein synonyms
Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, transient receptor potential vanilloid 1a, transient receptor potential vanilloid 1b, Vanilloid receptor 1, vanilloid receptor subtype 1
Uniprot ID
Q9NY22
Mouse ortholog
Trpv1 (193034)
transient receptor potential cation channel subfamily V member 1 (Q704Y3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 27 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3 adverse events reported
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